Over the first half of the fourth quarter, Methyldopa prices gradually increased at a moderate rate in North America. End-user demand from the pharmaceutical industry kept Methyldopa costs on the sturdy end. Additionally, there was a steep decline in supply chain disruption in the six months leading up to November across several measures, including shipping costs, which further strengthened the Methyldopa market in an upward direction. Prices for Methyldopa stayed on the North side till November when they were recorded at USD 159500 /MT CFR Los Angeles. However, towards the end of q4, they started to fall precipitously due to a major decrease in their offtakes.
In the fourth quarter of 2022, Methyldopa prices in the Asia Pacific area, particularly in China, sharply declined. However, prices remained on the upper side throughout the initial half of q4 due to increased downstream demand balanced with supplies among market participants. On the other hand, the ease in supply chain disruption in November compared to October, including the lower shipping costs, encouraged the traders and suppliers to raise their orders. With the year 2022 concluding, China's production activities started to decline, particularly after November, due to an increase in COVID-19 instances and a reduction in freight costs, supporting the price trend of Methyldopa in China. Overall, the Methyldopa costs noted in the middle of the fourth were assembled at USD 150655/MT FOB Shanghai in China.
The Methyldopa market in Europe followed a similar trajectory to that in Asia Pacific in the fourth quarter of 2022. Due to a rise in demand from the end-user pharmaceutical business, the market trend started off well up until November and reached an assembly price of USD 161850/MT CFR Hamburg in Germany. After December, Methyldopa pricing inquiries from the downstream industry started to decline dramatically, which reinforced the drug's weaker price trend because market participants had plenty of supply and little to no demand. Also, fresher quotations declined in December because of suppliers' high stock levels brought on by the market closure.
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